Description

(R)-(-)-1-[(R)-2-(2'-Diphenylphosphinophenyl)Ferrocenyl]Ethylbis(Di-3,5-Trifluoromethylphenyl)Phosphine is a highly specialized, chiral ferrocenyl phosphine ligand, a cornerstone in modern asymmetric catalysis. Its unique three-dimensional structure, featuring a ferrocene backbone and electron-withdrawing trifluoromethyl groups, provides exceptional stereocontrol and reactivity in transition metal-catalyzed reactions. This ligand is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop enantiomerically pure compounds with high efficiency and selectivity.

Application

• Asymmetric Hydrogenation: A premier ligand for the enantioselective reduction of prochiral olefins, ketones, and imines, critical for producing chiral intermediates in active pharmaceutical ingredients (APIs).
• Asymmetric C-C Bond Formation: Enables key transformations such as cross-coupling, allylic substitution, and hydroformylation with high enantiomeric excess (ee).
• Pharmaceutical Intermediate Synthesis: Used in the development of chiral drugs for cardiovascular, central nervous system, and oncological therapies.
• Agrochemical Production: Facilitates the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical and Fragrance Manufacturing: Applied in the creation of high-value chiral flavors, fragrances, and specialty chemicals.
• Catalyst Screening and Development: A valuable tool in R&D for discovering and optimizing new catalytic processes in academic and industrial laboratories.

Basic Information

Product Name	(R)-(-)-1-[(R)-2-(2'-Diphenylphosphinophenyl)Ferrocenyl]Ethylbis(Di-3,5-Trifluoromethylphenyl)Phosphine
CAS No.	565184-33-0
Molecular Formula	C55H38F12FeP2
Molecular Weight	1020.66 g/mol
Synonyms	(R,R)-TaniaPhos; TaniaPhos; (R)-(-)-1-[(R)-2-(Diphenylphosphino)ferrocenyl]ethyldi(3,5-bis(trifluoromethyl)phenyl)phosphine; (R,R)-1-[(R)-2-(2'-Diphenylphosphinophenyl)ferrocenyl]ethylbis(3,5-bis(trifluoromethyl)phenyl)phosphine; JosiPhos SL-J009-1; Chiral Ferrocenyl Diphosphine Ligand; Walphos SL-W001-1
EINECS	Contact for details

Quality Control

Every batch of (R)-(-)-1-[(R)-2-(2'-Diphenylphosphinophenyl)Ferrocenyl]Ethylbis(Di-3,5-Trifluoromethylphenyl)Phosphine is manufactured and analyzed under strict quality management systems to ensure exceptional purity and chiral integrity. Our products undergo rigorous quality testing, including chiral HPLC, NMR, and elemental analysis, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and full analytical data is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent oxidation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Orange to red powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Solubility	Soluble in common organic solvents (e.g., DCM, THF, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.