Description

(R)-(+)-1-[(R)-2-(2'-Diphenylphosphinophenyl)Ferrocenyl]Ethyldiphenylphosphine CAS NO 565184-32-9 is a highly specialized, chiral ferrocenyl diphosphine ligand, a cornerstone in modern asymmetric catalysis. Its value lies in its ability to impart exceptional enantioselectivity and catalytic activity in a range of transition metal-catalyzed reactions, enabling the efficient synthesis of single-enantiomer compounds. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require high-performance, reliable ligands for creating chiral intermediates and active ingredients.

Application

• As a privileged ligand in asymmetric hydrogenation reactions for the synthesis of chiral amino acids, alcohols, and pharmaceutical intermediates.
• Catalyst component for asymmetric C-C bond-forming reactions, including cross-coupling and allylic substitution.
• Key chiral inducer in the synthesis of high-value agrochemicals and flavor & fragrance compounds.
• Research and development of novel catalytic processes in academic and industrial laboratories.
• Process development and scale-up for the commercial production of single-enantiomer Active Pharmaceutical Ingredients (APIs).
• Used in conjunction with rhodium, iridium, or ruthenium complexes to achieve high enantiomeric excess (ee).

Basic Information

Item	Detail
Product Name	(R)-(+)-1-[(R)-2-(2'-Diphenylphosphinophenyl)Ferrocenyl]Ethyldiphenylphosphine
CAS No.	565184-32-9
Molecular Formula	C48H40FeP2
Molecular Weight	734.61 g/mol
Synonyms	(R,R)-TaniaPhos; (R,R)-TaniaPhos Ligand; (R,R)-1-[(R)-2-[2-(Diphenylphosphino)phenyl]ferrocenyl]ethyldiphenylphosphine; (R,R)-1-[(R)-2-(2'-Diphenylphosphino)phenyl]ferrocenyl]ethyldiphenylphosphine; JosiPhos Derivative; TaniaPhos Ligand; Chiral Ferrocenyl Diphosphine; (R,R)-TaniaPhos (C48H40FeP2)
EINECS	Contact for details

Quality Control

Every batch of our chiral ligands is produced and tested under strict quality management protocols to ensure consistent high performance. We provide comprehensive Certificates of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and identity confirmation. Our quality systems support development under cGMP guidelines for pharmaceutical applications, and we comply with relevant global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry place. Due to its sensitivity to oxidation, the container should only be opened in an inert glovebox or under a positive pressure of inert gas.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Solubility	Soluble in common organic solvents (DCM, THF, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.