Description

2-Chloro-N-[4-(2,5-difluorophenyl)-1,3-thiazol-2-yl]acetamide is a high-purity, advanced pharmaceutical intermediate featuring a unique thiazole core substituted with difluorophenyl and chloroacetamide functional groups. This compound is of significant value for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research targeting specific biological pathways. It is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new drug candidates, especially those targeting kinase inhibition or other enzyme-related activities.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced crop protection agents and herbicides.
• Organic Synthesis Reagent: Employed in academic and industrial labs for constructing complex heterocyclic molecules due to its reactive chloroacetamide moiety.
• Bioconjugation & Probe Development: Potential use in creating chemical probes for biochemical assays and diagnostic applications.

Basic Information

Item	Details
Product Name	2-Chloro-N-[4-(2,5-difluorophenyl)-1,3-thiazol-2-yl]acetamide
CAS No.	565172-39-6
Molecular Formula	C11H7ClF2N2OS
Molecular Weight	288.70 g/mol
Synonyms	2-Chloro-N-(4-(2,5-difluorophenyl)thiazol-2-yl)acetamide; Acetamide, 2-chloro-N-[4-(2,5-difluorophenyl)-2-thiazolyl]-; 2-Chloroacetamide, N-[4-(2,5-difluorophenyl)-1,3-thiazol-2-yl]-; 565172-39-6; 4-(2,5-Difluorophenyl)-2-[(2-chloroacetyl)amino]thiazole; N-(4-(2,5-Difluorophenyl)thiazol-2-yl)-2-chloroacetamide
EINECS	Contact for details

Quality Control

Our 2-Chloro-N-[4-(2,5-difluorophenyl)-1,3-thiazol-2-yl]acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to prevent exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.