Description

(2S)-2-Amino-3,3,3-trifluoro-1-propanol is a high-value, chiral fluorinated building block essential for modern synthetic chemistry. Its unique structure, featuring a trifluoromethyl group adjacent to an amino alcohol moiety, makes it a critical intermediate for introducing fluorine atoms into target molecules to modulate their physicochemical properties. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, where it serves as a key precursor for fluorinated amino acids, ligands, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Asymmetric Catalyst Ligand: Serves as a precursor for chiral ligands in metal-catalyzed asymmetric reactions, enabling the production of enantiomerically pure compounds.
• Fluorinated Amino Acid Analog: A building block for incorporating the 3,3,3-trifluoroalanine motif into peptides and proteins to study structure-activity relationships.
• Material Science Research: Employed in the development of specialty polymers and advanced materials with unique surface properties.
• Chemical Biology Probe: Utilized to create molecular probes for studying enzyme mechanisms and biological pathways involving fluorine interactions.

Basic Information

Product Name	(2S)-2-Amino-3,3,3-trifluoro-1-propanol
CAS No.	561323-79-3
Molecular Formula	C3H6F3NO
Molecular Weight	129.08 g/mol
Synonyms	(S)-2-Amino-3,3,3-trifluoropropanol; (S)-3,3,3-Trifluoroalaninol; L-3,3,3-Trifluoroalaninol; (2S)-3,3,3-Trifluoro-2-aminopropan-1-ol; 3,3,3-Trifluoro-L-alaninol; 1-Propanol, 2-amino-3,3,3-trifluoro-, (2S)-; (S)-(-)-2-Amino-3,3,3-trifluoro-1-propanol
EINECS	Contact for details

Quality Control

Our production of (2S)-2-Amino-3,3,3-trifluoro-1-propanol adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with each shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.