Description

1H-Pyrrolo[2,3-B]Pyridine-4-Carbonitrile, 1-Acetyl-2,3-Dihydro- is a high-purity, heterocyclic organic compound serving as a critical building block in advanced chemical synthesis. Its value lies in its unique fused pyrrolopyridine core, which is a privileged scaffold for developing novel active pharmaceutical ingredients (APIs) and functional materials. This intermediate is essential for research and production in pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate within nitrogen-containing heterocycle chemistry.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of kinase inhibitors, receptor antagonists, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in creating novel active ingredients for crop protection products, leveraging its heterocyclic structure for bioactivity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring complex, multi-step organic transformations.
• Academic & Industrial R&D: Fundamental building block for exploratory chemistry in medicinal and synthetic organic chemistry laboratories.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-4-Carbonitrile, 1-Acetyl-2,3-Dihydro-
CAS No.	561298-00-8
Molecular Formula	C10H9N3O
Molecular Weight	187.20 g/mol
Synonyms	1-Acetyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile; 4-Cyano-1-acetyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine; 1-Acetyl-1,2,3,4-tetrahydropyrrolo[2,3-b]pyridine-4-carbonitrile; Pyrrolo[2,3-b]pyridine-4-carbonitrile, 1-acetyl-2,3-dihydro-; 561298-00-8; 1-Acetyl-4-cyano-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-4-Carbonitrile, 1-Acetyl-2,3-Dihydro- is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.