Description

tert-Butyl ((1R,4R)-4-Morpholinocyclohexyl)Carbamate is a high-purity, chiral organic building block of significant interest in advanced pharmaceutical synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex, stereochemically defined molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, especially those targeting neurological and oncological pathways.
• Peptide Mimetic Research: Used in the design and construction of peptidomimetics and conformationally restricted analogs for medicinal chemistry programs.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying enzyme mechanisms and protein-protein interactions.
• Process Chemistry & Scale-Up: Provides a reliable, high-quality starting material for optimizing and scaling synthetic routes from laboratory to pilot plant scale.

Basic Information

Product Name	tert-Butyl ((1R,4R)-4-Morpholinocyclohexyl)Carbamate
CAS No.	558442-96-9
Molecular Formula	C15H28N2O3
Molecular Weight	284.40 g/mol
Synonyms	(1R,4R)-4-Morpholinocyclohexanamine, N-Boc derivative; tert-Butyl (1R,4R)-4-morpholinocyclohexylcarbamate; N-Boc-(1R,4R)-4-morpholinocyclohexylamine; (1R,4R)-N-(tert-Butoxycarbonyl)-4-morpholinocyclohexanamine; 4-Morpholinocyclohexanamine, N-[(1,1-dimethylethoxy)carbonyl]-, (1R,4R)-; BOC-(1R,4R)-4-Morpholinocyclohexylamine; (1R,4R)-4-(Morpholin-4-yl)cyclohexylcarbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl ((1R,4R)-4-Morpholinocyclohexyl)Carbamate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral HPLC for enantiomeric purity and identity confirmation by NMR and mass spectrometry. Certificates of Analysis (COA) detailing purity, chiral excess, and impurity profiles are provided with every shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.