Description

3,4-Dichlorophenylacetylene is a high-purity organic building block featuring a terminal alkyne group on a dichlorinated aromatic ring. This compound is valued for its role as a versatile synthon in advanced organic synthesis, particularly in cross-coupling reactions like the Sonogashira reaction. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, especially those requiring a rigid, halogenated aromatic core.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the dichlorophenyl moiety imparts specific biological activity.
• Material Science Research: Serves as a monomer or precursor in the development of conjugated polymers, organic semiconductors, and advanced materials.
• Cross-Coupling Reactions: An essential reagent for Sonogashira, Heck, and other palladium-catalyzed coupling reactions to form carbon-carbon bonds.
• Ligand and Catalyst Development: Used to synthesize specialized ligands for metal complexes and catalysts.
• Chemical Biology Probes: Employed in click chemistry applications to create labeled molecules for biological target identification.

Basic Information

Product Name	3,4-Dichlorophenylacetylene
CAS No.	556112-20-0
Molecular Formula	C8H4Cl2
Molecular Weight	171.03 g/mol
Synonyms	1,2-Dichloro-4-ethynylbenzene; (3,4-Dichlorophenyl)ethyne; 4-Ethynyl-1,2-dichlorobenzene; 3,4-Dichlorobenzeneacetylene; 3,4-DCPA
EINECS	Contact for details

Quality Control

Our 3,4-Dichlorophenylacetylene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications and results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Typical 98-99%)
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.