Description

1H-Pyrrolo[3,2-B]Pyridine-3-Acetonitrile is a high-purity nitrogen-containing heterocyclic building block, specifically a fused pyrrolopyridine derivative. This compound is valued for its versatile reactivity, particularly the nitrile functional group, which serves as a key synthetic handle for constructing complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	1H-Pyrrolo[3,2-B]Pyridine-3-Acetonitrile
CAS No.	554453-19-9
Molecular Formula	C9H7N3
Molecular Weight	157.17 g/mol
Synonyms	3-(Cyanomethyl)-1H-pyrrolo[3,2-b]pyridine; 1H-Pyrrolo[3,2-b]pyridine-3-acetonitrile; 3-(Cyanomethyl)-7-azaindole; 7-Azaindole-3-acetonitrile; Pyrrolo[3,2-b]pyridine-3-acetonitrile; 3-Cyanomethyl-1H-pyrrolo[3,2-b]pyridine; 1H-Pyrrolo(3,2-b)pyridine-3-acetonitrile
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[3,2-B]Pyridine-3-Acetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.