Description

9H-Carbazole, 1,8-Bis[(4S)-4,5-Dihydro-4-Phenyl-2-Oxazolyl]- is a sophisticated chiral ligand and building block derived from the carbazole scaffold. This compound matters for its role in facilitating asymmetric synthesis, where it acts as a key component in catalysts for creating enantiomerically pure molecules. It is needed by researchers and manufacturers in the pharmaceutical and fine chemical industries who require high-purity, specialized intermediates for advanced organic transformations.

Application

• Asymmetric Catalysis: Serves as a chiral ligand in transition metal-catalyzed reactions, such as asymmetric hydrogenation, allylic substitution, and cycloadditions.
• Pharmaceutical Intermediate: A key building block in the synthesis of complex, biologically active molecules requiring specific stereochemistry.
• Material Science Research: Used in the development of novel organic electronic materials, given the conductive properties of the carbazole core.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and catalysis studies within university and corporate laboratories.
• Fine Chemical Synthesis: Employed in the multi-step production of agrochemicals, flavors, and fragrances where enantioselectivity is critical.

Basic Information

Item	Detail
Product Name	9H-Carbazole, 1,8-Bis[(4S)-4,5-Dihydro-4-Phenyl-2-Oxazolyl]-
CAS No.	553663-64-2
Molecular Formula	C36H28N4O2
Molecular Weight	548.64 g/mol
Synonyms	1,8-Bis[(4S)-4,5-dihydro-4-phenyl-2-oxazolyl]-9H-carbazole; (S,S)-1,8-Bis(4-phenyl-4,5-dihydrooxazol-2-yl)carbazole; Carbazole-based bis(oxazoline) ligand; Chiral BOX ligand derivative; (S)-1,8-Bis(4-phenyl-2-oxazolin-2-yl)carbazole; (4S,4'S)-1,8-Bis(4-phenyl-4,5-dihydrooxazol-2-yl)-9H-carbazole
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized to confirm identity, purity, and enantiomeric excess, which is critical for performance in asymmetric synthesis. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), chiral purity, and residual solvent content are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.