Description

Abz-Ser-Pro-3-Nitro-Tyr-Oh CAS NO 553644-01-2 is a specialized, chemically modified peptide sequence featuring a nitrotyrosine residue, designed for advanced biochemical research and development. This compound serves as a critical tool for studying protein-protein interactions, enzyme kinetics, and signal transduction pathways where tyrosine nitration plays a regulatory role. It is essential for pharmaceutical researchers, proteomics laboratories, and academic institutions focused on oxidative stress, neurodegenerative diseases, and cardiovascular research.

Application

• Biochemical Research Reagent: Used as a substrate or inhibitor in enzymatic assays to study tyrosine nitration and its biological effects.
• Proteomics & Biomarker Discovery: Serves as a standard or reference compound in mass spectrometry for identifying and quantifying nitrotyrosine-containing proteins.
• Pharmaceutical Development: Employed in high-throughput screening (HTS) and drug discovery programs targeting pathways involving oxidative post-translational modifications.
• Antibody Production & Validation: Acts as a hapten for generating and characterizing specific antibodies against nitrotyrosine epitopes.
• Cell Signaling Studies: Utilized in cellular models to investigate the role of protein nitration in inflammation, apoptosis, and other signaling cascades.
• Academic Research: A key material for fundamental studies in biochemistry, neurobiology, and free radical biology.

Basic Information

Product Name	Abz-Ser-Pro-3-Nitro-Tyr-Oh
CAS No.	553644-01-2
Molecular Formula	C24H26N6O10
Molecular Weight	558.50 g/mol
Synonyms	Abz-Ser-Pro-Tyr(NO2)-OH; 2-Aminobenzoyl-L-seryl-L-prolyl-3-nitro-L-tyrosine; L-Tyrosine, N2-(2-aminobenzoyl)-L-seryl-L-prolyl-3-nitro-; Abz-SP-3-Nitro-Y-OH; Fluorescent Peptide Substrate with Nitrotyrosine; 3-Nitrotyrosine-containing Peptide; Nitrated Tyrosine Peptide; Research Peptide 553644-01-2
EINECS	Contact for details

Quality Control

Every batch of Abz-Ser-Pro-3-Nitro-Tyr-Oh is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, MS, and NMR, to ensure high purity and structural identity for research applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥95%
Assay	≥97%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.