Description

Phosphine, 1,1'-[(1S,3S)-1,3-Dimethyl-1,3-Propanediyl]Bis[1,1-Bis(3,5-Dimethylphenyl)- is a specialized organophosphorus compound featuring a chiral, sterically hindered backbone and multiple aromatic substituents. This unique molecular architecture makes it a valuable ligand precursor or catalyst component in advanced synthetic chemistry, particularly for asymmetric transformations. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of complex, high-value target molecules.

Application

• Asymmetric Catalysis: Serving as a chiral ligand or ligand precursor in transition metal-catalyzed reactions such as hydrogenation, hydroformylation, and cross-coupling.
• Pharmaceutical Intermediate Synthesis: A key building block in the research and development of novel active pharmaceutical ingredients (APIs) requiring stereochemical control.
• Agrochemical Research: Used in the synthesis of advanced crop protection agents and herbicides where specific stereochemistry is critical for activity.
• Material Science: Potential application as a monomer or additive in the development of specialty polymers with tailored properties.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and catalysis research.

Basic Information

Product Name	Phosphine, 1,1'-[(1S,3S)-1,3-Dimethyl-1,3-Propanediyl]Bis[1,1-Bis(3,5-Dimethylphenyl)-
CAS No.	551950-92-6
Molecular Formula	C39H48P2
Molecular Weight	578.73 g/mol
Synonyms	(1S,3S)-2,4-Bis[bis(3,5-dimethylphenyl)phosphino]-2,4-dimethylpentane; (S,S)-2,4-Bis[bis(3,5-dimethylphenyl)phosphino]-2,4-dimethylpentane; (S,S)-DIPAMP-DM; (S,S)-Bis(di-3,5-xylylphosphino)-2,4-dimethylpentane; Chiral Diphosphine Ligand; Sterically Hindered Diphosphine; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Every batch of this high-purity organophosphorus compound is produced and tested under strict quality management protocols. Standard quality control includes verification of chiral purity, chemical identity, and overall assay by advanced analytical techniques. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with each shipment to ensure it meets the exacting standards required for research and process development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity, keep away from strong oxidizers and ensure containers are sealed to prevent moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.