Description

n-(4-Bromo-2-Fluorophenyl)-3-Chloropropanamide is a specialized halogenated aromatic amide intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research and development chemists, process development scientists, and manufacturers engaged in creating active pharmaceutical ingredients (APIs), crop protection agents, and novel materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Synthesis: Serves as a key building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its halogenated aromatic structure.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or tagging reagent in the design of chemical probes and enzyme inhibitors for biological research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise halogenated motif.

Basic Information

Product Name	n-(4-Bromo-2-Fluorophenyl)-3-Chloropropanamide
CAS No.	551926-70-6
Molecular Formula	C9H8BrClFNO
Molecular Weight	280.52 g/mol
Synonyms	3-Chloro-N-(4-bromo-2-fluorophenyl)propanamide; 4-Bromo-2-fluoro-N-(3-chloropropanoyl)aniline; 1-(4-Bromo-2-fluorophenylamino)-3-chloropropan-1-one; Propanamide, N-(4-bromo-2-fluorophenyl)-3-chloro-; 551926-70-6; 4-Bromo-2-fluoroaniline-3-chloropropanamide derivative
EINECS	Contact for details

Quality Control

Our n-(4-Bromo-2-Fluorophenyl)-3-Chloropropanamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC for residual solvent analysis, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.