Description

n-(4-Bromo-2-Fluorophenyl)-2-Fluorobenzamide is a high-purity fluorinated aromatic amide building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and functional materials, where its specific halogen and fluorine substitution pattern enables precise molecular design. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and receptor antagonist research.
• Agrochemical Synthesis: Used as a building block for developing new herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Material Science Research: Serves as a monomer or functional component in the creation of specialty polymers and liquid crystals.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific projects requiring this unique halogenated benzamide structure.

Basic Information

Product Name	n-(4-Bromo-2-Fluorophenyl)-2-Fluorobenzamide
CAS No.	551906-53-7
Molecular Formula	C13H8BrF2NO
Molecular Weight	312.11 g/mol
Synonyms	2-Fluoro-N-(4-bromo-2-fluorophenyl)benzamide; 4'-Bromo-2'-fluoro-2-fluorobenzanilide; N-(4-Bromo-2-fluorophenyl)-2-fluorobenzoic acid amide; 2-Fluorobenzoic acid (4-bromo-2-fluorophenyl)amide; Benzamide, N-(4-bromo-2-fluorophenyl)-2-fluoro-; 551906-53-7; AKOS005258209
EINECS	Contact for details

Quality Control

Our n-(4-Bromo-2-Fluorophenyl)-2-Fluorobenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports your R&D and scale-up processes with reliable, traceable material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.