Description

Carbamic Acid, [(1R,4S)-4-Hydroxy-2-Cyclohexen-1-Yl]-, 1,1-Dimethylethyl Ester is a high-purity, chiral intermediate of significant importance in advanced organic synthesis. This compound is valued for its defined stereochemistry and functional groups, which make it a critical building block for constructing complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Asymmetric Synthesis: Utilized as a starting material or advanced intermediate in stereoselective reactions to introduce the (1R,4S)-configured cyclohexenyl moiety.
• Process Chemistry Development: Serves as a critical raw material for scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Protease Inhibitor Research: Potential building block for the development of enzyme inhibitors, leveraging its carbamate and hydroxy-cyclohexene structure.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, agrochemicals, and other high-value, low-volume products requiring precise stereochemical control.
• Academic & Contract Research: Employed in academic laboratories and CROs (Contract Research Organizations) for methodological studies and novel compound library generation.

Basic Information

Product Name	Carbamic Acid, [(1R,4S)-4-Hydroxy-2-Cyclohexen-1-Yl]-, 1,1-Dimethylethyl Ester
CAS No.	551000-83-0
Molecular Formula	C11H19NO3
Molecular Weight	213.27 g/mol
Synonyms	(1R,4S)-4-[(tert-Butoxycarbonyl)amino]-2-cyclohexen-1-ol; tert-Butyl N-[(1R,4S)-4-hydroxy-2-cyclohexen-1-yl]carbamate; (1R,4S)-4-(Boc-amino)-2-cyclohexen-1-ol; Boc-(1R,4S)-4-Amino-2-cyclohexen-1-ol; (1R,4S)-4-Hydroxy-2-cyclohexenylcarbamic acid tert-butyl ester; (1R,4S)-Boc-4-Amino-2-cyclohexen-1-ol; (1R,4S)-4-(tert-Butoxycarbonylamino)cyclohex-2-en-1-ol
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, [(1R,4S)-4-Hydroxy-2-Cyclohexen-1-Yl]-, 1,1-Dimethylethyl Ester adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting customer specifications and industry best practices. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.