Description

Acetamide, n-Methyl-n-(3S)-3-Pyrrolidinyl- (9Ci) is a chiral acetamide derivative featuring a pyrrolidine scaffold, a structure of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and process development of new therapeutic agents, particularly those targeting neurological and metabolic pathways.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs) for central nervous system (CNS) and metabolic disorder therapeutics.
• Asymmetric Synthesis Building Block: Utilized in the construction of complex, enantiomerically pure molecules for medicinal chemistry and drug discovery programs.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chiral ligands and organocatalysts used in stereoselective transformations.
• Agrochemical Research: Employed in the research and development of new, targeted crop protection agents with specific modes of action.
• Chemical Biology Probe Synthesis: Used to develop molecular probes for studying biological pathways and protein functions in academic and industrial research.
• Process Chemistry & Scale-Up: A critical material for optimizing synthetic routes and scaling up production from laboratory to pilot plant scale.

Basic Information

Product Name	Acetamide, n-Methyl-n-(3S)-3-Pyrrolidinyl- (9Ci)
CAS No.	550370-77-9
Molecular Formula	C7H14N2O
Molecular Weight	142.20 g/mol
Synonyms	N-Methyl-N-[(3S)-pyrrolidin-3-yl]acetamide; (S)-N-Methyl-N-(3-pyrrolidinyl)acetamide; (3S)-N-Methyl-N-(pyrrolidin-3-yl)acetamide; 1-(3S)-3-(Methylamino)pyrrolidin-1-yl]ethanone; Acetamide, N-methyl-N-[(3S)-3-pyrrolidinyl]-; (S)-1-(3-(Methylamino)pyrrolidin-1-yl)ethan-1-one; Pyrrolidine-3-carboxamide, N-methyl derivative (S-isomer); A key chiral pyrrolidine acetamide intermediate.
EINECS	Contact for details

Quality Control

Our production of Acetamide, n-Methyl-n-(3S)-3-Pyrrolidinyl- (9Ci) adheres to stringent quality protocols suitable for pharmaceutical R&D and process chemistry. Each batch is characterized and tested to ensure identity, purity, and chiral integrity. Certificates of Analysis (COA) are provided, detailing results for chiral purity (enantiomeric excess), chemical purity (HPLC), and other critical parameters. We support compliance with ICH guidelines for impurities and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed after opening to prevent degradation due to moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.