Description

Benzeneacetonitrile, 3-Fluoro-α-Hydroxy-, (-)- (9Ci) CAS NO 550313-06-9 is a chiral, fluorinated organic building block of significant interest in advanced synthetic chemistry. Its core value lies in its unique molecular architecture, combining a nitrile group, a fluorine substituent, and a chiral hydroxyl center, which makes it a versatile precursor for constructing complex, bioactive molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the fluorine atom and chiral center can enhance biological activity and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fluorinated fine chemicals and specialty materials.
• Academic and Industrial Research: A valuable tool for methodological studies in organic synthesis, particularly in exploring new fluorination and chiral induction pathways.

Basic Information

Product Name	Benzeneacetonitrile, 3-Fluoro-α-Hydroxy-, (-)- (9Ci)
CAS No.	550313-06-9
Molecular Formula	C9H8FNO
Molecular Weight	165.16 g/mol
Synonyms	(-)-3-Fluoro-α-hydroxybenzeneacetonitrile; (R)-2-(3-Fluorophenyl)-2-hydroxyacetonitrile; (R)-3-Fluoromandelonitrile; 3-Fluoro-α-hydroxybenzeneacetonitrile, (-)-; α-Hydroxy-3-fluorobenzeneacetonitrile; 2-(3-Fluorophenyl)-2-hydroxyacetonitrile; (R)-(-)-3-Fluoromandelonitrile; 3-Fluoromandelonitrile
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, chiral purity, and chemical purity. Certificates of Analysis (COA) are available upon request, detailing specifications such as enantiomeric excess (ee), assay, and impurity profiles. We adhere to strict internal quality management protocols to ensure batch-to-batch consistency for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Recommended storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.