Description

4-(Di-T-Boc-Aminomethyl)-3-Chlorobenzonitrile is a high-purity, protected amine intermediate used in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise molecular building blocks for complex molecule assembly. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing benzonitrile and protected amine functionalities.
• Peptide Mimetics & PROTACs: Serves as a versatile linker or spacer molecule in the design of peptide mimetics and Proteolysis-Targeting Chimeras (PROTACs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides, leveraging its chlorobenzonitrile core.
• Material Science Research: Employed in the creation of specialty polymers and functionalized materials that require specific amine-protected monomers.
• Chemical Biology Probes: Acts as a precursor for fluorescent tags, affinity labels, and other molecular probes used in biochemical research.
• Custom Synthesis & Scale-Up: An essential intermediate for contract research and manufacturing organizations (CROs/CMOs) offering custom synthesis services.

Basic Information

Product Name	4-(Di-T-Boc-Aminomethyl)-3-Chlorobenzonitrile
CAS No.	549531-00-2
Molecular Formula	C20H27ClN2O4
Molecular Weight	394.90 g/mol
Synonyms	4-[(Di-tert-butoxycarbonylamino)methyl]-3-chlorobenzonitrile; 3-Chloro-4-[(N,N-di-tert-butoxycarbonyl)aminomethyl]benzonitrile; 4-(Di-Boc-aminomethyl)-3-chlorobenzonitrile; 4-(Bis(tert-butoxycarbonyl)aminomethyl)-3-chlorobenzonitrile; 4-[(Bis(tert-butoxycarbonyl)amino)methyl]-3-chlorobenzonitrile; 4-[(N,N-Di-tert-butoxycarbonylamino)methyl]-3-chlorobenzonitrile; 4-(Di-T-Boc-Aminomethyl)-3-Chloro-Benzenecarbonitrile
EINECS	Contact for details

Quality Control

Our 4-(Di-T-Boc-Aminomethyl)-3-Chlorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.