Description

2-Amino-5-(1-methylethyl)benzonitrile is a specialized aromatic nitrile derivative featuring both an amino and an isopropyl substituent, making it a versatile intermediate for advanced synthesis. This compound matters for its role as a critical building block in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and functional dyes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides and fungicides, where its benzonitrile core contributes to biological activity.
• Functional Material Development: Serves as a monomer or building block for specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Industry: Employed in the production of high-performance, light-fast azo dyes and pigments.
• Research & Development: Utilized in academic and industrial R&D labs for method development and exploring new chemical entities.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	2-Amino-5-(1-methylethyl)benzonitrile
CAS No.	549488-76-8
Molecular Formula	C10H12N2
Molecular Weight	160.22 g/mol
Synonyms	2-Amino-5-isopropylbenzonitrile; 5-Isopropyl-2-aminobenzonitrile; 2-Cyano-4-isopropylaniline; 4-Isopropyl-2-aminobenzonitrile; Benzonitrile, 2-amino-5-(1-methylethyl)-; 2-Amino-α,α-dimethyl-p-tolunitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-5-(1-methylethyl)benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (HPLC), related substances, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.