Description

Boc-2-Methoxy-6-Methylaniline is a protected aniline derivative, specifically an N-Boc (tert-butoxycarbonyl) protected amine, which is a crucial building block in modern organic synthesis. This compound matters because it provides a stable, orthogonal protecting group for the primary amine, enabling selective reactions in complex multi-step syntheses, particularly in pharmaceutical development. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the production of active pharmaceutical ingredients (APIs), ligands, and functionalized polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders and oncology.
• Peptide & Protein Research: Used in solid-phase peptide synthesis (SPPS) to introduce protected aniline-containing amino acid analogs.
• Agrochemical Synthesis: Intermediate in the development of advanced herbicides, fungicides, and plant growth regulators.
• Material Science: Monomer or precursor for synthesizing specialty polymers, dyes, and photoactive materials.
• Chemical Biology: Useful for creating probes and linkers in bioconjugation and labeling strategies.
• Catalyst & Ligand Development: Serves as a precursor for nitrogen-containing ligands used in asymmetric catalysis.

Basic Information

Product Name	Boc-2-Methoxy-6-Methylaniline
CAS No.	545424-34-8
Molecular Formula	C₁₃H₁₉NO₃
Molecular Weight	237.29 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-2-methoxy-6-methylaniline; 2-Methoxy-6-methylaniline N-Boc derivative; tert-Butyl (2-methoxy-6-methylphenyl)carbamate; N-Boc-2-Methoxy-6-Methylaniline; Boc-2-Methoxy-6-Methylbenzenamine; (2-Methoxy-6-methylphenyl)carbamic acid tert-butyl ester; 1,1-Dimethylethyl N-(2-methoxy-6-methylphenyl)carbamate
EINECS	Contact for details

Quality Control

Our Boc-2-Methoxy-6-Methylaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting cGMP and ISO 9001 compliance for traceability and reliability in your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.