Description

1H-Pyrrolizine-7A(5H)-Carbonitrile,Tetrahydro-1,7-Dimethyl-,(1Alpha,7Alpha,7Aalpha)-(9Ci) is a high-purity, specialized organic compound with the CAS registry number 545402-47-9. This nitrile-functionalized pyrrolizine derivative serves as a critical advanced pharmaceutical intermediate and a versatile building block in synthetic organic chemistry. It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and fine chemical industries for developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those targeting neurological or metabolic pathways.
• Agrochemical Research: Building block for developing new generation pesticides and herbicides with specific modes of action.
• Fine Chemical Synthesis: Used in constructing complex heterocyclic compounds for material science and specialty chemical applications.
• Academic & Industrial R&D: Essential reagent for methodological studies in organic synthesis and catalysis.
• Ligand and Catalyst Development: Serves as a scaffold for creating novel ligands used in asymmetric catalysis.

Basic Information

Product Name	1H-Pyrrolizine-7A(5H)-Carbonitrile,Tetrahydro-1,7-Dimethyl-,(1Alpha,7Alpha,7Aalpha)-(9Ci)
CAS No.	545402-47-9
Molecular Formula	C10H14N2
Molecular Weight	162.23 g/mol
Synonyms	1,7-Dimethyl-1,2,3,5,6,7-hexahydropyrrolizin-7a-carbonitrile; Tetrahydro-1,7-dimethyl-1H-pyrrolizine-7a(5H)-carbonitrile; 7a-Cyano-1,7-dimethylhexahydropyrrolizine; 545402-47-9; (1α,7α,7aα)-Tetrahydro-1,7-dimethyl-1H-pyrrolizine-7a-carbonitrile
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.