Description

Bicyclo[2.1.1]Hexane-1-Carboxamide, 5,5-Dimethyl-, (1R,4R)- (9Ci) is a high-purity, stereochemically defined bicyclic carboxamide building block of significant interest in advanced organic synthesis. Its rigid, three-dimensional scaffold is engineered to impart unique conformational and steric properties to target molecules, making it a critical intermediate for medicinal chemistry and materials science research. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel drug candidates, particularly in programs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where its bicyclic structure can enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Employed as a precursor for creating sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Precursor: Functions as a monomer or cross-linking agent in the synthesis of polymers with specific thermal or mechanical properties.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying enzyme function and protein-ligand interactions.
• Process Chemistry & Scale-Up: Supplied for route scouting, optimization, and pilot-scale production of target molecules under GMP or ISO guidelines.

Basic Information

Item	Detail
Product Name	Bicyclo[2.1.1]Hexane-1-Carboxamide, 5,5-Dimethyl-, (1R,4R)- (9Ci)
CAS No.	544693-87-0
Molecular Formula	C9H15NO
Molecular Weight	153.22 g/mol
Synonyms	(1R,4R)-5,5-Dimethylbicyclo[2.1.1]hexane-1-carboxamide; (1R,4R)-5,5-Dimethyl-1-bicyclo[2.1.1]hexanecarboxamide; 5,5-Dimethylbicyclo[2.1.1]hexane-1-carboxamide, (1R,4R)-; Bicyclo[2.1.1]hexane-1-carboxamide, 5,5-dimethyl-, (1R,4R)-; (1R,4R)-rel-5,5-Dimethylbicyclo[2.1.1]hexane-1-carboxamide; (1R,4R)-5,5-Dimethyl-1-aminocarbonylbicyclo[2.1.1]hexane
EINECS	Contact for details

Quality Control

Our Bicyclo[2.1.1]Hexane-1-Carboxamide, 5,5-Dimethyl-, (1R,4R)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including chiral HPLC, NMR, and LC-MS to confirm identity, stereochemical purity, and chemical purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can adhere to ISO 9001 standards, and material for pharmaceutical applications can be supplied under appropriate GMP guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.