Description

4-Fluoro-N,n-Diisopropylbenzenesulfonamide is a high-purity, specialized sulfonamide derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which combines a fluorinated aromatic ring with diisopropyl-substituted sulfonamide functionality, enabling precise modifications in target molecules. It is primarily utilized by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of next-generation herbicides and fungicides, where the fluorine atom and sulfonamide group contribute to biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor or functional component in the creation of specialized ligands for transition metal catalysis and organocatalysts.
• Material Science: Potential monomer or additive in the synthesis of specialty polymers with tailored thermal or chemical resistance properties.
• Chemical Biology Probe Synthesis: Employed in creating molecular probes for studying enzyme function and protein-ligand interactions due to its modifiable scaffold.

Basic Information

Product Name	4-Fluoro-N,n-Diisopropylbenzenesulfonamide
CAS No.	544460-63-1
Molecular Formula	C12H18FNO2S
Molecular Weight	259.34 g/mol
Synonyms	N,N-Diisopropyl-4-fluorobenzenesulfonamide; 4-Fluoro-N,N-diisopropylbenzenesulfonamide; p-Fluoro-N,N-diisopropylbenzenesulfonamide; Benzenesulfonamide, 4-fluoro-N,N-bis(1-methylethyl)-; 1-Fluoro-4-[(diisopropylsulfamoyl)methyl]benzene (alternative); 4-Fluoro-N,N-diisopropylphenylsulfonamide
EINECS	Contact for details

Quality Control

Our 4-Fluoro-N,n-Diisopropylbenzenesulfonamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.