Description

1,1Bis((2R,5R)-2,5-Dimethylphospholano)Ferrocene, Min. 97% is a high-purity, chiral ferrocenyl phosphine ligand, a crucial component in asymmetric catalysis. This compound matters because it enables the precise control of stereochemistry in the synthesis of complex pharmaceutical intermediates and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require highly selective and efficient catalytic processes.

Application

• Asymmetric Hydrogenation: A key chiral ligand for the enantioselective reduction of prochiral olefins, ketones, and imines in pharmaceutical synthesis.
• Pharmaceutical Intermediate Synthesis: Used in the catalytic production of chiral active pharmaceutical ingredients (APIs) for drugs targeting central nervous system, cardiovascular, and metabolic diseases.
• Agrochemical Manufacturing: Facilitates the creation of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Enables asymmetric carbon-carbon and carbon-heteroatom bond-forming reactions for high-value fragrance and flavor ingredients.
• Academic & Industrial R&D: Serves as a benchmark ligand in method development for new catalytic transformations in organic chemistry.
• Catalyst Screening Libraries: A vital component in high-throughput screening kits for identifying optimal catalytic conditions.

Basic Information

Product Name	1,1Bis((2R,5R)-2,5-Dimethylphospholano)Ferrocene, Min. 97%
CAS No.	540475-45-4
Molecular Formula	C22H32FeP2
Molecular Weight	414.26 g/mol
Synonyms	(R,R)-1,1'-Bis(2,5-dimethylphospholano)ferrocene; Josiphos SL-J009-1; (R,R)-DMe-DuPhos-Ferrocene; (R,R)-1,1'-Bis[(2R,5R)-2,5-dimethylphospholanyl]ferrocene; (R,R)-1,1'-Bis(2,5-dimethylphospholan-1-yl)ferrocene; (R,R)-DMe-DuPhos-Fc; Chiral Ferrocenyl Diphosphine Ligand; (R,R)-DMe-DuPhos-Ferrocene Ligand
EINECS	Contact for details

Quality Control

Our 1,1Bis((2R,5R)-2,5-Dimethylphospholano)Ferrocene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure a minimum purity of 97% and correct stereochemical configuration. Certificates of Analysis (COA) with full analytical data are provided to guarantee consistency and traceability for your critical catalytic applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to prevent oxidation and degradation. Allow the container to reach room temperature in a dry environment before opening to minimize moisture exposure.

Specification

Item	Specification
Appearance	Orange to red-brown solid
Identification (IR)	Conforms to structure
Purity (HPLC)	Min. 97.0%
Enantiomeric Excess (Chiral HPLC)	Min. 99.0% ee
Water Content (KF)	Max. 0.5%
Residue on Ignition	Max. 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.