Description

2-Pyrimidinecarbonitrile,5-Phenoxy-(9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its pyrimidine core for bioactivity.
• Material Science: Acts as a building block for creating advanced organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke chemicals for client projects.
• Academic Research: Utilized in university and institutional laboratories for methodological development and exploring new chemical reactions involving nitrile and phenoxy functional groups.

Basic Information

Product Name	2-Pyrimidinecarbonitrile,5-Phenoxy-(9Ci)
CAS No.	540463-68-1
Molecular Formula	C11H7N3O
Molecular Weight	197.19 g/mol
Synonyms	5-Phenoxy-2-pyrimidinecarbonitrile; 5-Phenoxypyrimidine-2-carbonitrile; 2-Cyano-5-phenoxypyrimidine; Phenoxy-substituted pyrimidinecarbonitrile; 5-Phenoxy-2-cyanopyrimidine; 540463-68-1; 5-Phenoxy-pyrimidine-2-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Pyrimidinecarbonitrile,5-Phenoxy-(9Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment. We can support development projects requiring material that meets ICH guidelines for impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.