Description

Benzamide, n-(3,4-Dihydro-2H-1-Benzopyran-3-Yl)-, (+)- (9Ci) is a high-purity chiral benzamide derivative, a key building block in advanced organic synthesis. Its defined stereochemistry and specific molecular architecture make it a valuable intermediate for creating complex, biologically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors who require precise, high-quality intermediates for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Research: Used in the synthesis of advanced crop protection agents and herbicides, leveraging its benzopyran scaffold.
• Chemical Biology Probe: Acts as a scaffold or precursor for developing molecular probes to study enzyme function and protein-ligand interactions.
• Asymmetric Catalysis: Employed as a ligand precursor or a test substrate in the development of new chiral catalysts and synthetic methodologies.
• Material Science Research: Investigated as a monomer or functional component for creating specialty polymers with specific optical or electronic properties.

Basic Information

Item	Detail
Product Name	Benzamide, n-(3,4-Dihydro-2H-1-Benzopyran-3-Yl)-, (+)- (9Ci)
CAS No.	539857-57-3
Molecular Formula	C16H15NO2
Molecular Weight	253.30 g/mol
Synonyms	(+)-N-(3,4-Dihydro-2H-1-benzopyran-3-yl)benzamide; (3R)-3,4-Dihydro-2H-1-benzopyran-3-amine, N-benzoyl-, (3R)-; (R)-N-(Chroman-3-yl)benzamide; Benzamide, N-(3,4-dihydro-2H-1-benzopyran-3-yl)-, (R)-; (R)-N-(3,4-Dihydro-2H-chromen-3-yl)benzamide; 539857-57-3; UNII-9FZ6L5177T
EINECS	Contact for details

Quality Control

Every batch of Benzamide, n-(3,4-Dihydro-2H-1-Benzopyran-3-Yl)-, (+)- (9Ci) is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and enantiomeric excess meet the stringent requirements of research and development. A detailed Certificate of Analysis (COA) including results for assay, chiral purity, and related substances is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.