Description

(1R,2R,4R,5R)-2,5-Bis(3,5-Di-tert-Butyl-2-Hydroxybenzylideneamino)Bicyclo[2.2.1]Heptane is a high-purity, chiral Schiff base ligand with a complex bicyclic norbornane core structure. This compound matters for its exceptional ability to act as a chelating agent and stereoselective catalyst in advanced organic synthesis and materials science. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, fine chemical, and advanced materials sectors for developing novel catalytic systems and chiral intermediates.

Application

• Asymmetric Catalysis: A key chiral ligand for transition metal-catalyzed asymmetric reactions, including hydrogenation, epoxidation, and C-C bond formation.
• Pharmaceutical Intermediate Synthesis: Used in the stereoselective synthesis of complex, bioactive molecules and active pharmaceutical ingredients (APIs).
• Polymerization Catalyst Component: Serves as a co-catalyst or ligand in the synthesis of stereoregular polymers and specialty plastics.
• Materials Science Research: Employed in the development of metal-organic frameworks (MOFs), molecular sensors, and functionalized surfaces.
• Analytical Chemistry: Can be used as a chiral selector or complexing agent in chromatography and spectroscopy.
• Academic & Industrial R&D: A valuable tool for investigating new catalytic pathways and reaction mechanisms in organic chemistry.

Basic Information

Product Name	(1R,2R,4R,5R)-2,5-Bis(3,5-Di-tert-Butyl-2-Hydroxybenzylideneamino)Bicyclo[2.2.1]Heptane
CAS No.	539834-19-0
Molecular Formula	C39H58N2O2
Molecular Weight	586.89 g/mol
Synonyms	(1R,2R,4R,5R)-2,5-Bis[(3,5-di-tert-butyl-2-hydroxyphenyl)methyleneamino]bicyclo[2.2.1]heptane; Norbornane Schiff Base Ligand; Chiral Salen-Type Ligand; (R,R,R,R)-Bicyclo[2.2.1]heptane-2,5-diylbis[(3,5-di-tert-butyl-2-hydroxybenzylidene)amine]; BINOL-Norbornane Hybrid Ligand; 539834-19-0; CAS 539834-19-0
EINECS	Contact for details

Quality Control

Our (1R,2R,4R,5R)-2,5-Bis(3,5-Di-tert-Butyl-2-Hydroxybenzylideneamino)Bicyclo[2.2.1]Heptane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chiral purity and chemical identity, with specifications typically meeting or exceeding research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and identification data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat, sparks, and open flame. The container must be kept tightly sealed to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.