Description

4-Fluoro-2-(Trifluoromethyl)Phenacyl Bromide is a versatile and highly functionalized organic bromide building block. This compound matters for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides and pesticides, leveraging the fluorine and trifluoromethyl groups for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of advanced organic electronic materials and liquid crystals due to its unique electronic properties imparted by the fluorine atoms.
• Chemical Biology Probes: Useful for synthesizing activity-based probes and tags for studying enzyme function and protein labeling.
• Custom Synthesis & Contract Manufacturing: A key raw material for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	4-Fluoro-2-(Trifluoromethyl)Phenacyl Bromide
CAS No.	537050-13-8
Molecular Formula	C9H5BrF4O
Molecular Weight	285.04 g/mol
Synonyms	2-Bromo-1-(4-fluoro-2-(trifluoromethyl)phenyl)ethan-1-one; 1-(4-Fluoro-2-(trifluoromethyl)phenyl)-2-bromoethanone; α-Bromo-4'-fluoro-2'-(trifluoromethyl)acetophenone; 4-Fluoro-α-bromo-2-(trifluoromethyl)acetophenone; Phenacyl bromide, 4-fluoro-2-(trifluoromethyl)-; 537050-13-8; Bromo(4-fluoro-2-(trifluoromethyl)phenyl)methanone
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-(Trifluoromethyl)Phenacyl Bromide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in a desiccated environment away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.