Description

tert-Butyl 2-(2-(pyridin-2-yl)disulfanyl)ethylcarbamate is a specialized organic compound featuring a disulfide linkage and a protected amine group, making it a valuable intermediate in synthetic chemistry. Its core value lies in its role as a versatile building block for constructing complex molecules, particularly in the development of pharmaceuticals and bioactive compounds. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and life science industries who require high-purity intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring disulfide or thiol-protected functionalities.
• Peptide Chemistry & Bioconjugation: Used in the synthesis and modification of peptides, proteins, and antibodies, leveraging its cleavable disulfide linker for controlled release or targeted delivery systems.
• Protecting Group Chemistry: Serves as a reagent for introducing the tert-butoxycarbonyl (Boc) protecting group to amines under specific conditions, facilitated by its reactive disulfide moiety.
• Cross-linking Agent: Utilized in material science and polymer chemistry to create cross-linked networks or functionalized surfaces via disulfide bond formation.
• Research & Development: A critical tool in medicinal chemistry for exploring structure-activity relationships (SAR) and developing new drug candidates with sulfur-containing pharmacophores.
• Agrochemical Synthesis: Employed as an intermediate in the production of certain herbicides, fungicides, or plant growth regulators.

Basic Information

Product Name	tert-Butyl 2-(2-(pyridin-2-yl)disulfanyl)ethylcarbamate
CAS No.	535943-48-7
Molecular Formula	C12H18N2O2S2
Molecular Weight	286.41 g/mol
Synonyms	2-({2-[(tert-Butoxycarbonyl)amino]ethyl}disulfanyl)pyridine; N-(tert-Butoxycarbonyl)-2-(2-pyridinyldithio)ethylamine; Boc-AEEA-PySS; 2-Pyridyldithio ethylamine Boc derivative; tert-Butyl N-[2-[(2-pyridinyl)dithio]ethyl]carbamate; 2-(2-Boc-aminoethyl)disulfanyl pyridine; Pyridin-2-yl 2-((tert-butoxycarbonyl)amino)ethyl disulfide
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(2-(pyridin-2-yl)disulfanyl)ethylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.