Description

4-Trifluoromethylphenylthioethanol is a high-value organosulfur and organofluorine building block characterized by its trifluoromethylphenyl and thioethanol functional groups. This compound is essential for introducing specific lipophilicity and metabolic stability into target molecules, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing drug candidates, particularly those targeting central nervous system (CNS) disorders, where the trifluoromethyl group can enhance blood-brain barrier penetration.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its ability to modify the biological activity and environmental persistence of active compounds.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating specialized fluorinated components used in display technologies and organic electronics.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, altering surface properties, chemical resistance, and durability for high-performance coatings and materials.
• Ligand & Catalyst Development: Utilized in organometallic chemistry to create novel ligands for catalysis, benefiting from the electron-withdrawing nature of the trifluoromethyl group.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in medicinal chemistry, material science, and fluorine chemistry.

Basic Information

Product Name	4-Trifluoromethylphenylthioethanol
CAS No.	535937-56-5
Molecular Formula	C9H9F3OS
Molecular Weight	222.23 g/mol
Synonyms	2-[(4-Trifluoromethyl)phenyl]thio]ethanol; 2-[(4-(Trifluoromethyl)phenyl)thio]ethan-1-ol; 4-(Trifluoromethyl)thiophenethyl alcohol; 2-[(4-Trifluoromethylphenyl)sulfanyl]ethanol; α-(4-Trifluoromethylthiophenyl)ethanol; 4-Trifluoromethyl-β-mercaptophenethyl alcohol; (4-Trifluoromethylphenylthio)ethanol
EINECS	Contact for details

Quality Control

Our 4-Trifluoromethylphenylthioethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.