Description

2-Thiopheneacetonitrile, 4-(Hydroxymethyl)- (9Ci) is a versatile heterocyclic building block featuring both a nitrile and a hydroxymethyl functional group on a thiophene core. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients, as well as by material scientists exploring functional polymers and organic electronics.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the thiophene ring's bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Functional Material Research: Employed in the synthesis of monomers for conductive polymers, organic semiconductors, and nonlinear optical (NLO) materials.
• Chemical Biology Probes: Useful for synthesizing labeled compounds or molecular probes for studying biological processes.
• Fine Chemical Production: Acts as a building block for various specialty chemicals, including dyes, pigments, and complex fragrances.

Basic Information

Product Name	2-Thiopheneacetonitrile, 4-(Hydroxymethyl)- (9Ci)
CAS No.	533939-49-0
Molecular Formula	C7H7NOS
Molecular Weight	153.20 g/mol
Synonyms	4-(Hydroxymethyl)thiophene-2-acetonitrile; (4-Hydroxymethyl-2-thienyl)acetonitrile; 2-Thiopheneacetonitrile, 4-(hydroxymethyl)-; 4-(Hydroxymethyl)-2-thiopheneacetonitrile; 2-Cyanoethyl-4-hydroxymethylthiophene; 4-Hydroxymethylthiophene-2-ylacetonitrile; α-(4-Hydroxymethyl-2-thienyl)acetonitrile
EINECS	Contact for details

Quality Control

Our 2-Thiopheneacetonitrile, 4-(Hydroxymethyl)- (9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports applications requiring high-purity intermediates under GMP or ISO-guided environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.