Description

5-Bromo-2-[[[[3-(4-Chlorophenyl)-1-Oxo-2-Propenyl]Amino]Thioxomethyl]Amino]-Benzoic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters because it provides a critical, structurally defined building block essential for research and development in medicinal chemistry, enabling the creation of novel therapeutic agents. It is primarily needed by pharmaceutical manufacturers, biotechnology R&D laboratories, and fine chemical synthesis specialists working on innovative drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel small-molecule drug candidates, particularly in oncology and anti-inflammatory research.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probe Synthesis: Employed in the development of molecular probes to study biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom synthesis projects and the production of specialized fine chemicals under cGMP conditions.
• Academic Research: Utilized in university and institutional laboratories for advanced organic synthesis methodologies and heterocyclic chemistry studies.

Basic Information

Product Name	5-Bromo-2-[[[[3-(4-Chlorophenyl)-1-Oxo-2-Propenyl]Amino]Thioxomethyl]Amino]-Benzoic Acid
CAS No.	532423-48-6
Molecular Formula	C17H12BrClN2O3S
Molecular Weight	439.71 g/mol
Synonyms	5-Bromo-2-[[[[3-(4-chlorophenyl)-1-oxo-2-propen-1-yl]amino]thioxomethyl]amino]benzoic acid; 2-[[[(3-(4-Chlorophenyl)-1-oxo-2-propenyl)amino]thioxomethyl]amino]-5-bromobenzoic acid; Benzoic acid, 5-bromo-2-[[[[3-(4-chlorophenyl)-1-oxo-2-propenyl]amino]thioxomethyl]amino]-; (E)-5-Bromo-2-((3-(4-chlorophenyl)acryloyl)carbamothioylamino)benzoic acid; CAS 532423-48-6
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-[[[[3-(4-Chlorophenyl)-1-Oxo-2-Propenyl]Amino]Thioxomethyl]Amino]-Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.