Description

(2S)-n-[(1R,2S)-2-Hydroxy-1,2-Diphenylethyl]-2-Pyrrolidinecarboxamide is a high-purity chiral compound of significant interest in advanced organic synthesis. This molecule matters as a sophisticated chiral building block or ligand, enabling the precise control of stereochemistry in the production of complex active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing enantiomerically pure products.

Application

• Asymmetric Synthesis Catalyst/Chiral Ligand: Employed as a key component in transition metal catalysis for enantioselective transformations such as hydrogenations, oxidations, and C-C bond formations.
• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the multi-step synthesis of novel drug candidates targeting central nervous system (CNS) disorders, infectious diseases, and metabolic conditions.
• Agrochemical Research: Used in the development of enantiomerically pure pesticides and herbicides, where specific stereochemistry is crucial for efficacy and environmental safety.
• Methodology Development: A valuable reference standard and tool compound for academic and industrial research focused on new catalytic systems and synthetic methodologies.
• Fine Chemical Production: Applied in the custom synthesis of high-value, complex molecules for electronics, materials science, and other advanced technology applications.

Basic Information

Item	Details
Product Name	(2S)-n-[(1R,2S)-2-Hydroxy-1,2-Diphenylethyl]-2-Pyrrolidinecarboxamide
CAS No.	529486-23-5
Molecular Formula	C19H22N2O2
Molecular Weight	310.40 g/mol
Synonyms	(S)-N-[(1R,2S)-2-Hydroxy-1,2-diphenylethyl]pyrrolidine-2-carboxamide; (S)-N-[(1R,2S)-2-Hydroxy-1,2-diphenylethyl]-2-pyrrolidinecarboxamide; (S)-N-[(1R,2S)-2-Hydroxy-1,2-diphenylethyl]prolinamide; (S)-Proline Amide Derivative; Chiral Prolinamide Ligand; (S)-N-[(1R,2S)-2-Hydroxy-1,2-diphenylethyl]-L-prolinamide
EINECS	Contact for details

Quality Control

Our (2S)-n-[(1R,2S)-2-Hydroxy-1,2-Diphenylethyl]-2-Pyrrolidinecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, NMR for structural confirmation, and assays for chemical purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications to ensure compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.