Description

3-Iodo-5,5,6,6,6-Pentafluorohexan-1-Ol is a specialized fluorinated building block that combines an alcohol functionality with a perfluorinated alkyl iodide segment. This unique structure makes it a valuable intermediate for introducing fluorinated motifs into target molecules, enhancing properties like lipophilicity, metabolic stability, and chemical resistance. It is primarily sought by researchers and process chemists in the pharmaceutical and advanced materials sectors for applications in medicinal chemistry, agrochemical development, and the synthesis of specialty surfactants or polymers.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly where fluorination is employed to improve bioavailability and metabolic stability.
• Agrochemical Research: Serves as a key building block for developing new active ingredients with enhanced environmental persistence and efficacy.
• Material Science: Employed in the creation of fluorinated polymers, coatings, and surfactants that require oil, water, and chemical resistance.
• Liquid Crystal & OLED Development: Acts as a precursor for fluorinated components in electronic display materials.
• Radiolabeling Precursor: The iodine atom provides a potential handle for further modification or radiolabeling studies.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed reactions (e.g., Sonogashira, Heck) to incorporate fluorinated chains into complex organic frameworks.

Basic Information

Product Name	3-Iodo-5,5,6,6,6-Pentafluorohexan-1-Ol
CAS No.	526223-11-0
Molecular Formula	C6H6F5IO
Molecular Weight	315.99 g/mol
Synonyms	5,5,6,6,6-Pentafluoro-3-iodo-1-hexanol; 3-Iodo-5,5,6,6,6-pentafluorohexanol; 1-Hexanol, 5,5,6,6,6-pentafluoro-3-iodo-; 5,5,6,6,6-Pentafluoro-3-iodohexan-1-ol; Pentafluoro-3-iodohexanol; 3-Iodo-5,5,6,6,6-pentafluoro-hexan-1-ol
EINECS	Contact for details

Quality Control

Our 3-Iodo-5,5,6,6,6-Pentafluorohexan-1-Ol is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and GC, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. For custom synthesis projects, we adhere to cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.