Description

o-Demethyl-n-Bis-Demethyl Tramadol is a key pharmaceutical intermediate and reference standard of significant importance in research and development. This compound is primarily utilized for analytical and synthetic purposes within the pharmaceutical and life sciences sectors. It is essential for laboratories and manufacturers involved in the development, quality control, and metabolic studies of analgesic compounds.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of related compounds via HPLC, GC-MS, and other chromatographic methods.
• Metabolite Research: Serves as a critical standard in pharmacokinetic and metabolic pathway studies for tramadol and its analogs.
• Analytical Method Development: Employed in the development and validation of new testing protocols in quality control laboratories.
• Chemical Synthesis: Acts as a high-purity building block or precursor in the synthesis of specialized pharmaceutical compounds and novel chemical entities.
• Forensic Analysis: Used as an analytical standard in forensic toxicology for the identification and quantification of substances.

Basic Information

Product Name	o-Demethyl-n-Bis-Demethyl Tramadol
CAS No.	522648-42-6
Molecular Formula	C15H23NO2
Molecular Weight	249.35 g/mol
Synonyms	N,N-Bisdesmethyltramadol; O-Desmethyl-N,N-bisdesmethyltramadol; 2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol; Tramadol Metabolite M5; 1-(3-Methoxyphenyl)-2-[(dimethylamino)methyl]cyclohexan-1-ol
EINECS	Contact for details

Quality Control

Our o-Demethyl-n-Bis-Demethyl Tramadol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the rigorous standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.