Description

Benzenepropanenitrile, 4-Fluoro-β-Hydroxy-, (Betar)- (9Ci) is a specialized chiral intermediate featuring a fluorinated aromatic ring and a nitrile functional group. This compound is valued for its role as a key building block in the synthesis of complex, biologically active molecules, offering precise stereochemical control. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs), particularly in areas such as central nervous system (CNS) agents and other fluorinated drug candidates.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel fluorinated pharmaceutical compounds.
• Agrochemical Synthesis: Used in the production of advanced, high-performance pesticides and herbicides where the fluorine atom enhances biological activity and stability.
• Liquid Crystal & OLED Material Research: Serves as a precursor in the synthesis of fluorinated organic electronic materials for displays and lighting.
• Asymmetric Catalysis Studies: Employed as a substrate or ligand precursor in academic and industrial research focused on developing new catalytic methodologies.
• Fine Chemical Manufacturing: Utilized in custom synthesis and contract manufacturing for producing high-value, complex organic molecules.

Basic Information

Product Name	Benzenepropanenitrile, 4-Fluoro-β-Hydroxy-, (Betar)- (9Ci)
CAS No.	522629-15-8
Molecular Formula	C9H8FNO
Molecular Weight	165.17 g/mol
Synonyms	(R)-4-Fluoro-β-hydroxybenzenepropanenitrile; (R)-3-(4-Fluorophenyl)-3-hydroxypropanenitrile; (R)-3-Hydroxy-3-(4-fluorophenyl)propionitrile; 4-Fluoro-β-hydroxybenzenepropanenitrile, (R)-; β-Hydroxy-4-fluorobenzenepropanenitrile, (R)-; (R)-3-(4-Fluorophenyl)-3-hydroxypropionitrile; (R)-3-(p-Fluorophenyl)-3-hydroxypropionitrile
EINECS	Contact for details

Quality Control

Our production of Benzenepropanenitrile, 4-Fluoro-β-Hydroxy-, (Betar)- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.