Description

Pth (1-84) (Rat) is a synthetic peptide fragment corresponding to the N-terminal 1-84 sequence of rat parathyroid hormone. This high-purity biochemical is essential for advanced research into calcium homeostasis, bone metabolism, and endocrine signaling pathways. It is a critical reagent for scientists in pharmaceutical R&D, academic research, and biotechnology focusing on metabolic bone diseases and peptide hormone function.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of parathyroid hormone (PTH) receptor binding, signaling cascades, and biological activity.
• Drug Discovery & Development: Serves as a key intermediate or reference compound in the screening and development of novel therapeutics for osteoporosis, hyperparathyroidism, and related disorders.
• In Vitro & In Vivo Assays: Employed in cell-based assays and animal model studies to investigate PTH's role in calcium and phosphate regulation.
• Analytical Standard: Utilized in quality control laboratories for method development, validation, and calibration in HPLC, MS, or immunoassay platforms.
• Peptide Chemistry Studies: Acts as a substrate for studying peptide stability, modification, and structure-activity relationships (SAR).

Basic Information

Product Name	Pth (1-84) (Rat)
CAS No.	521986-16-3
Molecular Formula	C390H637N117O118S2
Molecular Weight	~ 9.4 kDa
Synonyms	Rat Parathyroid Hormone (1-84); rPTH(1-84); Parathyrin (1-84), rat; PTH, rat; Rat PTH; Parathyroid hormone fragment 1-84 (rat); Endocrine peptide PTH (rat); CAS 521986-16-3
EINECS	Contact for details

Quality Control

Our Pth (1-84) (Rat) is manufactured under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, peptide content, and endotoxin levels are provided to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Endotoxin	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.