Description

Pth (1-84) (Dog) is a synthetic peptide fragment corresponding to the first 84 amino acids of the canine parathyroid hormone. This high-purity biochemical is critical for research into calcium metabolism and endocrine function in veterinary and comparative medicine. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on metabolic bone disease studies and therapeutic development for canine health.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of canine parathyroid hormone receptor (PTH1R) binding and signaling pathways.
• Veterinary Pharmacology: Serves as a key intermediate in the development and testing of novel therapeutics for conditions like hypoparathyroidism and renal osteodystrophy in dogs.
• Assay Development: Essential for the calibration and validation of immunoassays (ELISA, RIA) designed to measure PTH levels in canine serum samples.
• Comparative Endocrinology: Facilitates cross-species studies to understand the structural and functional evolution of parathyroid hormone.
• Peptide Chemistry Studies: Used in research exploring peptide stability, formulation, and delivery methods specific to veterinary applications.

Basic Information

Product Name	Pth (1-84) (Dog)
CAS No.	521986-14-1
Molecular Formula	C~390~H~637~N~117~O~118~S~2
Molecular Weight	Approx. 9127.2 g/mol
Synonyms	Canine Parathyroid Hormone (1-84); Dog PTH (1-84); PTH, canine; Parathyrin (1-84), canine; cPTH(1-84); Canine PTH full-length peptide; Parathyroid hormone fragment 1-84 (Dog)
EINECS	Contact for details

Quality Control

Every batch of Pth (1-84) (Dog) is manufactured and analyzed under strict quality management systems. Our products undergo rigorous quality testing, including reversed-phase HPLC and mass spectrometry, to ensure high purity and correct sequence verification. Certificates of Analysis (COA) detailing purity, peptide content, and analytical data are provided with each shipment to support your research compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture absorption. Aliquot into single-use vials after reconstitution to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular weight confirmed by mass spectrometry
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.