Description

3-Cyano-4-Fluorophenylacetic Acid is a high-purity, multi-functional chemical intermediate of significant importance in advanced organic synthesis. Its core value lies in its unique molecular structure, which combines a reactive cyano group, a fluorine substituent, and an acetic acid moiety, making it a versatile building block for creating complex molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to construct active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel small-molecule drugs, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for functionalized aromatic compounds used in electronic display technologies.
• Peptidomimetics & Bio-conjugation: The carboxylic acid group enables coupling reactions to create peptide analogs or for labeling biomolecules.
• Organic Synthesis Research: Employed in academic and industrial R&D for methodology development and the synthesis of complex fluorinated and cyanated aromatic targets.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific fluorophenylacetic acid derivatives.

Basic Information

Product Name	3-Cyano-4-Fluorophenylacetic Acid
CAS No.	519059-11-1
Molecular Formula	C9H6FNO2
Molecular Weight	179.15 g/mol
Synonyms	4-Fluoro-3-cyanophenylacetic acid; (4-Fluoro-3-cyanophenyl)acetic acid; 2-(4-Fluoro-3-cyanophenyl)acetic acid; 3-Cyano-4-fluorobenzeneacetic acid; α-(4-Fluoro-3-cyanophenyl)acetic acid; 519059-11-1; 4-Fluoro-3-cyanobenzeneacetic acid
EINECS	Contact for details

Quality Control

Our 3-Cyano-4-Fluorophenylacetic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.