Description

2-Amino-4-(4-Isopropylphenyl)-5-Methylthiophene-3-Carbonitrile is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a thiophene ring with an amino and a nitrile group, making it a versatile precursor for constructing complex pharmacophores and functional materials. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for drug discovery and specialty chemical manufacturing.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Research: Acts as a monomer or precursor for the development of organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to its electron-rich thiophene structure.
• Dye and Pigment Chemistry: Employed in the synthesis of specialized dyes and pigments where the thiophene moiety contributes to color stability and specific light-absorption properties.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry, including studies on cyclization reactions and heterocycle functionalization.

Basic Information

Product Name	2-Amino-4-(4-Isopropylphenyl)-5-Methylthiophene-3-Carbonitrile
CAS No.	519016-80-9
Molecular Formula	C15H16N2S
Molecular Weight	256.37 g/mol
Synonyms	2-Amino-4-(4-isopropylphenyl)-5-methylthiophene-3-carbonitrile; 5-Methyl-2-amino-4-(4-isopropylphenyl)thiophene-3-carbonitrile; 4-(4-Isopropylphenyl)-2-amino-5-methylthiophene-3-carbonitrile; 2-Amino-4-(p-isopropylphenyl)-5-methyl-3-thiophenecarbonitrile; 3-Cyano-2-amino-4-(4-isopropylphenyl)-5-methylthiophene; Thiophene-3-carbonitrile, 2-amino-4-[4-(1-methylethyl)phenyl]-5-methyl-; CAS 519016-80-9
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(4-Isopropylphenyl)-5-Methylthiophene-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the high standards required for research and cGMP-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.