Description

tert-Butyl (R)-(1-(Naphthalen-1-Yl)Ethyl)Carbamate is a high-purity, chiral organic building block of significant importance in advanced pharmaceutical synthesis. This compound serves as a key chiral intermediate, enabling the construction of complex molecules with defined stereochemistry. It is primarily required by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of active pharmaceutical ingredients (APIs) and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the research and production of enantiomerically pure Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Used as a building block in stereoselective reactions to introduce the (R)-1-(naphthalen-1-yl)ethylamine moiety.
• Medicinal Chemistry Research: Employed in the discovery and optimization of new drug candidates, particularly in central nervous system (CNS) and oncology research.
• Peptidomimetics & PROTACs: Serves as a component in the synthesis of peptide mimics and Proteolysis-Targeting Chimeras (PROTACs) due to its bulky, aromatic group.
• Catalyst & Ligand Preparation: Can be utilized for the synthesis of chiral ligands and organocatalysts for asymmetric catalysis.
• Fine Chemical Production: Applied in the custom synthesis of specialty chemicals requiring high enantiomeric purity.

Basic Information

Product Name	tert-Butyl (R)-(1-(Naphthalen-1-Yl)Ethyl)Carbamate
CAS No.	518335-32-5
Molecular Formula	C₁₇H₂₁NO₂
Molecular Weight	271.35 g/mol
Synonyms	(R)-1-(1-Naphthyl)ethyl carbamic acid tert-butyl ester; tert-Butyl N-[(1R)-1-(1-naphthyl)ethyl]carbamate; (R)-tert-Butyl (1-(naphthalen-1-yl)ethyl)carbamate; (R)-1-(1-Naphthyl)ethylamine N-Boc protected; Boc-(R)-1-(1-Naphthyl)ethylamine; N-Boc-(R)-1-(1-Naphthyl)ethylamine; (R)-N-Boc-1-(1-Naphthalenyl)ethanamine; (R)-N-(tert-Butoxycarbonyl)-1-(1-naphthyl)ethylamine
EINECS	Contact for details

Quality Control

Our tert-Butyl (R)-(1-(Naphthalen-1-Yl)Ethyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity compliant with research and pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.