Description

1,4-Methanocyclopenta[C]Pyrrole-1(2H)-Carbonitrile,Hexahydro-3A,6A-Dimethyl-,(1R,3As,4R,6Ar)-(9Ci) is a high-purity, stereochemically defined organic compound of significant interest in advanced chemical synthesis. This molecule serves as a sophisticated building block and key intermediate for the development of novel active compounds. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating new molecular entities with targeted biological activity.

Application

This specialized chemical intermediate is designed for high-value synthetic applications. Its primary uses include:

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Research: Used as a building block for developing new active ingredients in crop protection and pest management products.
• Chemical Biology Probe Synthesis: Employed in the construction of molecular probes for studying biological pathways and target validation.
• Asymmetric Synthesis: Utilized as a chiral scaffold or auxiliary in stereoselective synthesis due to its defined stereochemistry.
• Medicinal Chemistry: Serves as a core structure for structure-activity relationship (SAR) studies and lead optimization programs.
• Process Chemistry Development: Acts as a key intermediate in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	1,4-Methanocyclopenta[C]Pyrrole-1(2H)-Carbonitrile,Hexahydro-3A,6A-Dimethyl-,(1R,3As,4R,6Ar)-(9Ci)
CAS No.	518314-75-5
Molecular Formula	C11H16N2
Molecular Weight	176.26 g/mol
Synonyms	(1R,3aS,4R,6aR)-Hexahydro-3a,6a-dimethyl-1,4-methanocyclopenta[c]pyrrole-1-carbonitrile; (1R,3aS,4R,6aR)-Hexahydro-3a,6a-dimethyl-1,4-methanocyclopenta[c]pyrrole-1-carbonitrile (9CI); 1,4-Methanocyclopenta[c]pyrrole-1-carbonitrile, hexahydro-3a,6a-dimethyl-, (1R,3aS,4R,6aR)-; 518314-75-5; 1,4-Methanocyclopenta[C]Pyrrole-1(2H)-Carbonitrile,Hexahydro-3A,6A-Dimethyl-,(1R,3As,4R,6Ar)-; (1R,3aS,4R,6aR)-3a,6a-Dimethyloctahydro-1,4-methanocyclopenta[c]pyrrole-1-carbonitrile
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ analytical techniques including HPLC, GC, and NMR for comprehensive characterization. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. Our quality system is designed to support cGMP requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.