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2-Fluoro-4-Methylphenylacetic Acid CAS NO 518070-28-5


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CAS No.:518070-28-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Fluoro-4-Methylphenylacetic Acid is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both a carboxylic acid and a fluorine substituent on the phenyl ring, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought by R&D and production teams in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

  • Pharmaceutical Intermediate: A key synthon in the research and production of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic motifs for enhanced metabolic stability and bioavailability.
  • Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atom can improve lipophilicity and target binding.
  • Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in display and lighting technologies.
  • Fine Chemical & Specialty Polymer Production: Employed in the synthesis of complex dyes, pigments, and specialty polymers that benefit from the unique electronic properties of the fluorine substituent.
  • Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and carboxylate derivatization.

Basic Information

Product Name 2-Fluoro-4-Methylphenylacetic Acid
CAS No. 518070-28-5
Molecular Formula C9H9FO2
Molecular Weight 168.16 g/mol
Synonyms (2-Fluoro-4-methylphenyl)acetic acid; 2-(2-Fluoro-4-methylphenyl)acetic Acid; 4-Methyl-2-fluorophenylacetic Acid; α-(2-Fluoro-4-methylphenyl)acetic Acid; 2-Fluoro-4-methylbenzeneacetic Acid; 2-Fluoro-p-tolylacetic Acid; FMPAA; 518070-28-5
EINECS Contact for details

Quality Control

We maintain stringent quality control protocols for all our fluorinated intermediates. Production follows current Good Manufacturing Practice (cGMP) principles where applicable, and each batch is analyzed to meet exacting purity standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically ≥97% by HPLC), and impurity profiles is provided with every shipment to ensure traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 97.0%
Melting Point Contact for details
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals < 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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