Description

5-Amino-2-Fluorophenylacetic Acid 98% is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern enables precise molecular design. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and pesticides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptide Mimetics and Conjugates: The phenylacetic acid moiety allows for incorporation into peptide backbones to create modified peptides with improved metabolic stability.
• Fluorescent Probe and Dye Chemistry: Utilized in the synthesis of advanced organic dyes and molecular probes for diagnostic and imaging applications.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.

Basic Information

Product Name	5-Amino-2-Fluorophenylacetic Acid 98%
CAS No.	518057-74-4
Molecular Formula	C8H8FNO2
Molecular Weight	169.15 g/mol
Synonyms	2-Fluoro-5-aminophenylacetic Acid; (5-Amino-2-fluorophenyl)acetic Acid; 2-Fluoro-5-aminobenzeneacetic Acid; 5-Amino-2-fluorobenzeneacetic Acid; 2-(5-Amino-2-fluorophenyl)acetic Acid; 518057-74-4; 5-Amino-2-fluorophenylacetic acid
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Fluorophenylacetic Acid 98% is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the specified 98% minimum purity and is free from critical impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.