Description

(E)-3-(1H-Benzo[D]Imidazol-1-Yl)-n-(4-Hydroxybenzylidene)Propanehydrazide CAS NO 518018-66-1 is a high-purity, synthetic organic compound featuring a benzimidazole core linked to a hydroxybenzylidene hydrazide moiety. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for research in medicinal chemistry. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis sectors for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition or receptor modulation.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities.
• Biochemical Probe Development: Used in the design and synthesis of probes for studying biological pathways and target identification.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to introduce the benzimidazole-hydrazone pharmacophore.
• Agrochemical Research: Potential intermediate for developing new crop protection agents with specific biological activity.

Basic Information

Product Name	(E)-3-(1H-Benzo[D]Imidazol-1-Yl)-n-(4-Hydroxybenzylidene)Propanehydrazide
CAS No.	518018-66-1
Molecular Formula	C18H17N5O2
Molecular Weight	335.36 g/mol
Synonyms	(E)-N'-(4-Hydroxybenzylidene)-3-(1H-benzimidazol-1-yl)propanehydrazide; 3-(1H-Benzimidazol-1-yl)-N-[(E)-(4-hydroxyphenyl)methylidene]propanehydrazide; 1H-Benzimidazole-1-propanoylhydrazone, 4-hydroxybenzaldehyde; 518018-66-1; Benzimidazole Hydrazone Derivative; 4-Hydroxybenzaldehyde (1H-Benzimidazol-1-yl)propionylhydrazone
EINECS	Contact for details

Quality Control

Our production of (E)-3-(1H-Benzo[D]Imidazol-1-Yl)-n-(4-Hydroxybenzylidene)Propanehydrazide adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets precise customer specifications. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.