Description

2-Bromo-4-Ethoxy-5-Methoxy-Benzonitrile is a high-purity, multi-functional benzonitrile derivative serving as a critical synthetic intermediate. Its value lies in its unique halogenated and alkoxy-substituted aromatic structure, which provides versatile reactivity for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators, leveraging its halogen and ether functionalities.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing specialized aromatic cores used in electronic display technologies and organic light-emitting diodes.
• Organic Synthesis & Chemical Research: A versatile reagent for Suzuki-Miyaura and other cross-coupling reactions, as well as nucleophilic aromatic substitution, in academic and industrial R&D laboratories.
• Dye & Pigment Intermediate: Employed in the development of specialized dyes and pigments due to its substituted benzonitrile backbone.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	2-Bromo-4-Ethoxy-5-Methoxy-Benzonitrile
CAS No.	515846-45-4
Molecular Formula	C10H10BrNO2
Molecular Weight	256.10 g/mol
Synonyms	5-Methoxy-2-bromo-4-ethoxybenzonitrile; 4-Ethoxy-5-methoxy-2-bromobenzonitrile; 2-Bromo-4-ethoxy-5-methoxybenzonitrile; Benzonitrile, 2-bromo-4-ethoxy-5-methoxy-; 515846-45-4; 2-Bromo-4-ethoxy-5-methoxy-benzonitrile
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Ethoxy-5-Methoxy-Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing batch-specific results. Our quality commitment supports applications requiring high-purity intermediates, from research to commercial-scale GMP production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.