Description

2-Bromo-4-Isopropoxy-5-Methoxy-Benzonitrile is a high-purity, multi-functional aromatic nitrile building block designed for advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Serves as a key precursor for developing advanced herbicides, fungicides, and insecticides, leveraging its substituted benzonitrile core.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its aromatic structure and functional groups.
• Chemical Research & Development: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to create diverse chemical libraries.
• Fine Chemical Production: Acts as an intermediate for synthesizing dyes, pigments, and other performance chemicals requiring specific bromo- and alkoxy-substituted aromatic systems.

Basic Information

Product Name	2-Bromo-4-Isopropoxy-5-Methoxy-Benzonitrile
CAS No.	515846-11-4
Molecular Formula	C11H12BrNO2
Molecular Weight	270.12 g/mol
Synonyms	5-Methoxy-2-bromo-4-isopropoxybenzonitrile; 4-Isopropoxy-5-methoxy-2-bromobenzonitrile; Benzonitrile, 2-bromo-4-(1-methylethoxy)-5-methoxy-; 2-Bromo-4-isopropoxy-5-methoxybenzonitrile; 2-Bromo-4-(1-methylethoxy)-5-methoxybenzonitrile
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Isopropoxy-5-Methoxy-Benzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.