Description

tert-Butyl 3-Phenylprop-2-Ynylcarbamate is a specialized carbamate-protected alkyne building block used in advanced organic synthesis. This compound is valued for its role as a key intermediate in the construction of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications such as medicinal chemistry, peptide mimetics, and material science.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring alkyne functionality for click chemistry or further derivatization.
• Medicinal Chemistry: Used in the research and development of new therapeutic agents, enabling the exploration of structure-activity relationships (SAR) through modular synthesis.
• Peptidomimetics & Bioconjugation: Serves as a protected alkyne handle for the synthesis of peptide mimics or for bioconjugation strategies in chemical biology.
• Agrochemical Synthesis: An intermediate in the development of novel crop protection agents and pesticides.
• Material Science Research: Employed in the synthesis of specialized monomers or polymers with tailored properties.
• Academic & Industrial R&D: A valuable reagent for method development and exploratory synthesis in university and corporate research laboratories.

Basic Information

Product Name	tert-Butyl 3-Phenylprop-2-Ynylcarbamate
CAS No.	512785-77-2
Molecular Formula	C14H17NO2
Molecular Weight	231.29 g/mol
Synonyms	N-Boc-3-Phenylpropargylamine; tert-Butyl (3-phenyl-2-propyn-1-yl)carbamate; Carbamic acid, N-(3-phenyl-2-propynyl)-, 1,1-dimethylethyl ester; Boc-3-phenylpropargylamine; 2-Propyn-1-amine, 3-phenyl-, N-[(1,1-dimethylethoxy)carbonyl]-; N-(tert-Butoxycarbonyl)-3-phenyl-2-propyn-1-amine; 3-Phenyl-2-propynylcarbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Phenylprop-2-Ynylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.