Description

(R)-tert-Butyl 3-Amino-4-Oxo-4-(((R)-1-Phenylethyl)Amino)Butanoate CAS NO 512785-16-9 is a high-purity chiral intermediate featuring a unique amino acid ester structure with two stereogenic centers. This compound is critical for ensuring the stereochemical integrity and efficacy of advanced pharmaceutical active ingredients. It is primarily utilized by research institutions and manufacturers in the pharmaceutical industry for the development and production of enantiomerically pure drugs, particularly in oncology and metabolic disease research.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex, enantiomerically pure active pharmaceutical ingredients (APIs).
• Protease Inhibitor Synthesis: Used in the research and development of novel protease inhibitors for therapeutic applications.
• Peptidomimetic Chemistry: Serves as a crucial component in the design and synthesis of peptidomimetics, which mimic peptides for drug discovery.
• Asymmetric Synthesis: Employed in catalytic and stoichiometric asymmetric reactions to introduce specific chiral configurations.
• Chemical Biology Research: Utilized as a molecular tool for studying enzyme-substrate interactions and biological pathways.
• Process Chemistry Development: Acts as a standard or reference material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.

Basic Information

Product Name	(R)-tert-Butyl 3-Amino-4-Oxo-4-(((R)-1-Phenylethyl)Amino)Butanoate
CAS No.	512785-16-9
Molecular Formula	C16H24N2O3
Molecular Weight	292.38 g/mol
Synonyms	(R)-tert-Butyl 3-amino-4-oxo-4-(((R)-1-phenylethyl)amino)butanoate; (R)-tert-Butyl 3-amino-4-(((R)-1-phenylethyl)amino)-4-oxobutanoate; (R)-3-Amino-4-oxo-4-(((R)-1-phenylethyl)amino)butanoic acid tert-butyl ester; Butanoic acid, 3-amino-4-oxo-4-(((1R)-1-phenylethyl)amino)-, 1,1-dimethylethyl ester, (3R)-; (3R)-3-Amino-4-oxo-4-{[(1R)-1-phenylethyl]amino}butanoic acid tert-butyl ester; tert-Butyl (3R)-3-amino-4-oxo-4-{[(1R)-1-phenylethyl]amino}butanoate
EINECS	Contact for details

Quality Control

Our (R)-tert-Butyl 3-Amino-4-Oxo-4-(((R)-1-Phenylethyl)Amino)Butanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high enantiomeric purity and chemical identity. Certificates of Analysis (COA) detailing purity, chiral excess, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere to prevent degradation. For long-term storage, consider storing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.