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(R)-(tert-Butylmethylphosphino-Di-tert-Butylphosphinomethane)Diborane CAS NO 512184-96-2


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CAS No.:512184-96-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(R)-(tert-Butylmethylphosphino-Di-tert-Butylphosphinomethane)Diborane is a highly specialized organophosphorus-borane complex used as a chiral ligand precursor or catalyst in advanced synthetic chemistry. This compound matters for its ability to impart stereoselectivity in critical bond-forming reactions, enabling the production of enantiomerically pure intermediates. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who require high-precision asymmetric synthesis.

Application

  • As a chiral ligand precursor for transition metal catalysts in asymmetric hydrogenation and cross-coupling reactions.
  • In the synthesis of enantiomerically pure pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
  • For the development of novel agrochemicals requiring specific stereochemistry for biological activity.
  • As a reagent in academic and industrial R&D for exploring new methodologies in organometallic chemistry.
  • In the production of specialty fine chemicals and advanced materials where stereochemical control is paramount.
  • For catalyst screening and optimization in process development for cost-effective scale-up.

Basic Information

Product Name (R)-(tert-Butylmethylphosphino-Di-tert-Butylphosphinomethane)Diborane
CAS No. 512184-96-2
Molecular Formula C15H37B2P2
Molecular Weight 292.02 g/mol
Synonyms (R)-tert-Butylmethylphosphino-Di-tert-butylphosphinomethanediborane; (R)-Bis(tert-butylmethylphosphino)methane Diborane Complex; (R)-DTBM-Diborane; (R)-tBu-MiniPHOS Diborane Adduct; (R)-1,1'-Methylenebis(tert-butylmethylphosphine) Diborane; Chiral Phosphine-Borane Complex; Ligand Precursor 512184-96-2
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Quality Control

Our (R)-(tert-Butylmethylphosphino-Di-tert-Butylphosphinomethane)Diborane is manufactured under strict quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with every shipment, supporting compliance with rigorous R&D and cGMP standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Due to its moisture-sensitive (hygroscopic) and easily oxidized nature, this material must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Keep the container sealed and handle in a controlled, moisture-free environment.

Specification

Item Specification
Appearance White to off-white solid
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Enantiomeric Excess (Chiral HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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