Description

Ertumaxomab is a trifunctional bispecific monoclonal antibody designed for targeted cancer immunotherapy. Its unique mechanism of action enables the simultaneous engagement of tumor cells and immune effector cells, facilitating a potent and localized anti-tumor response. This product is primarily utilized in advanced pharmaceutical research and development for novel oncology therapeutics, targeting specific antigens expressed on certain cancer cells.

Application

• Oncology Research & Drug Development: A key investigational agent in the development of next-generation immunotherapies for solid tumors.
• Preclinical & Clinical Studies: Used in in vitro and in vivo models to evaluate efficacy, pharmacokinetics, and mechanism of action.
• Targeted Cancer Therapy: Exploits its bispecific design to redirect T-cells and accessory immune cells to the tumor site.
• Immuno-Oncology Platforms: Serves as a reference or tool compound for developing similar trifunctional antibody platforms.
• Biopharmaceutical Manufacturing: Relevant for process development and scale-up activities for biologic APIs.
• Cell-Based Assays: Used in functional assays to study immune cell activation and tumor cell killing.

Basic Information

Product Name	Ertumaxomab
CAS No.	509077-99-0
Molecular Formula	Contact for details
Molecular Weight	Approx. 150 kDa (Contact for details)
Synonyms	Anti-CD3 x Anti-HER2/neu Trifunctional Bispecific Antibody; Rexomun; Trifunctional Antibody catumaxomab analogue; Ertumaxomab (USAN); UNII-6R430F6P8K
EINECS	Contact for details

Quality Control

Our Ertumaxomab is produced and controlled under a stringent quality management system. Each batch is subjected to a comprehensive panel of analytical tests to ensure identity, purity, potency, and safety, adhering to relevant ICH guidelines for biopharmaceuticals. A detailed Certificate of Analysis (COA) documenting purity (by HPLC/SEC), endotoxin levels, sterility, and biological activity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted or liquid formulations should be stored as directed in the specific product literature, typically at 2-8°C. The product is hygroscopic (moisture-sensitive); protect from humidity during handling.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (HPLC/LC-MS)	Conforms to reference standard
Purity (SEC-HPLC)	≥ 95.0% (Monomer)
Protein Content (UV/A280)	As per COA
Potency (Cell-based assay)	As per COA
Endotoxin	< 1.0 EU/mg
Sterility	Sterile
Moisture Content (KF)	≤ 3.0% (for lyophilized form)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.